Are negative symptoms in schizophrenia a distinct therapeutic target?

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Are negative symptoms in schizophrenia a distinct therapeutic target?

Background and aims The relationship between negative symptoms and cognition in schizophrenia is not clear, inconsistent findings have been reported by multiple authors and meta analyses. The aim of this study was to investigate the relationship between cognition and primary negative symptoms. Methods 67 outpatients diagnosed with schizophrenia were evaluated using PANSS and the NSA-16 scale....

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The Therapeutic Effectiveness of Risperidone on Negative Symptoms of Schizophrenia in Comparison with Haloperidol: A Randomized Clinical Trial

Introduction: A number of research studies have shown that the new generation of neuroleptic medications can more effectively contribute to treating negative symptoms of schizophrenia compared with the first generation by influence cognitive functioning. The present study examined the therapeutic effectiveness of manufactured Risperidone and Haloperidol in Iran on treating the negative symptoms...

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The Effects of Bupropion on Negative Symptoms in Schizophrenia

Abstract:Purpose:This study was designed determine the efficacy of bupropion versus placebo in subjects with negative symptoms of schizophrenia.Methods:A convenience sample of 40 patients of both genders aged 18-60 years who were living in psychiatric care centers were randomly treated with bupropion (started with 75 mg twice a day; increased to 100 mg thrice daily) or placebo. The diagnosis of...

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The Effects of Bupropion on Negative Symptoms in Schizophrenia

Abstract:Purpose:This study was designed determine the efficacy of bupropion versus placebo in subjects with negative symptoms of schizophrenia.Methods:A convenience sample of 40 patients of both genders aged 18-60 years who were living in psychiatric care centers were randomly treated with bupropion (started with 75 mg twice a day; increased to 100 mg thrice daily) or placebo. The diagnosis of...

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Negative symptoms in schizophrenia

The negative symptoms have been described in association with schizophrenia since the early days of it being recognized as an entity. However, their elusive nature kept them unacknowledged until there was a revival of interest in them following the development of specific quantifying measures. Over the past three decades, there has been a tremendous surge in research on their types, measurement...

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ژورنال

عنوان ژورنال: Medicine and Pharmacy Reports

سال: 2018

ISSN: 2668-0572,2602-0807

DOI: 10.15386/cjmed-864